Clomiphene Citrate (Clomid) 50 mg

Clomiphene Citrate (Clomid) 50 mg is Hilma Biocare's selective oestrogen receptor modulator, supplied as 50 tablets. It blocks oestrogen feedback in the hypothalamus and pituitary, raising gonadotropins and supporting natural testosterone production.

What Clomiphene Citrate Is

Clomiphene citrate is a non-steroidal SERM that binds oestrogen receptors and acts as an antagonist in the hypothalamus and pituitary while having mixed agonist and antagonist effects elsewhere. By blocking oestrogen feedback at those central sites, it increases gonadotropin-releasing hormone, LH and FSH output. That cascade stimulates testicular Leydig cells and supports endogenous testosterone production. The 50 mg tablet is the classic clinical strength.

The History of Clomid

Clomiphene was synthesised in the late 1950s by Merrell and approved in 1967 as Clomid for ovulation induction. It became one of the first widely used fertility drugs and remains a standard treatment for anovulation. Its ability to raise gonadotropins also made it a subject of research into male hypogonadism and post-suppression recovery, where it is now one of the most studied SERMs.

How It Works

Clomiphene binds oestrogen receptors in the hypothalamus and pituitary, preventing oestradiol from exerting negative feedback. The pituitary responds by secreting more LH and FSH, which in turn stimulate gonadal function. The drug is a mixture of two isomers, enclomiphene and zuclomiphene, which have different half-lives and receptor activities. It is metabolised in the liver and excreted mainly in bile and urine, with a prolonged terminal half-life.

What the Research Shows

• Clomiphene has been studied extensively for ovulation induction and male hypogonadism.
• Trials show increases in LH, FSH and total testosterone in men with secondary hypogonadism.
• Comparative work has examined clomiphene against testosterone replacement.
• The two-isomer composition and its differing pharmacology are well documented.

Research Context

Clomiphene's two-isomer composition explains much of its clinical behaviour. Zuclomiphene has a much longer half-life and stronger oestrogenic activity, while enclomiphene drives the gonadotropin response. That is why clomiphene can produce both the desired increase in LH and FSH and unwanted oestrogenic effects. Early ovulation-induction trials established the 50 mg dose, and later research examined extended regimens in anovulatory women. Visual disturbances and hot flushes are the most frequently reported effects, and they are usually reversible after the drug is stopped.

Strength, Pack and Authentication

The pack contains 50 tablets of 50 mg each, sealed in moisture-resistant blister strips inside a printed carton. The carton states the compound, strength and tablet count, and a scratch-off security code inside the box can be verified against Hilma Biocare's records. Each tablet delivers a consistent 50 mg dose.

Buying Clomid Online

Clomid is one of the most searched SERMs worldwide. If you are researching clomiphene citrate, comparing Clomid 50 mg products or looking to buy clomiphene online from a trusted Hilma Biocare supplier, this page gives you the full specification, pack size, price and live stock status. Browse more Hilma Biocare hormone-support products at NotNatty.