Mesterolone (Proviron) 25 mg

Mesterolone (Proviron) 25 mg is Hilma Biocare's oral dihydrotestosterone derivative, supplied as 50 tablets. It does not aromatise and binds sex hormone binding globulin, which is why it is studied as a free-testosterone support compound.

What Mesterolone Is

Mesterolone is an orally active DHT derivative with a methyl group at carbon one and a keto group at carbon three. Those changes make it resistant to metabolism and unable to aromatise. Its defining pharmacological feature is affinity for sex hormone binding globulin: mesterolone occupies SHBG and displaces testosterone, increasing the free fraction of the hormone. The 25 mg tablet is the classic Proviron strength.

The History of Proviron

Mesterolone was developed by Schering in the 1950s and introduced in the 1960s as Proviron. It was used clinically for androgen deficiency and as an adjunct in male fertility, where its effect on free testosterone was of interest. It never became a mass-building compound, and that is precisely why it found a niche as a support agent in hormone research rather than a primary anabolic.

How It Works

Mesterolone binds the androgen receptor directly and is not aromatised, so it adds androgenic activity without oestrogen. By occupying SHBG, it reduces the binding of testosterone to that protein and raises the free, biologically active fraction. It is not 17-alpha-alkylated in the same way as most oral steroids, which gives it a different hepatic profile. It is metabolised in the liver and excreted mainly in urine.

What the Research Shows

• Mesterolone has been studied in androgen deficiency and male fertility.
• Research shows it increases free testosterone by displacing it from SHBG.
• Its lack of aromatisation is well documented.
• Comparative work places it among the mildest oral androgens.

Research Context

Mesterolone's interaction with sex hormone binding globulin is the focus of most of its research. By occupying SHBG, it increases the free fraction of testosterone without adding an aromatisable substrate, which is an unusual combination among oral androgens. Studies in male fertility have examined its effects on sperm parameters and on free testosterone, with mixed results. Its lack of 17-alpha-alkylation in the usual sense gives it a different hepatic profile from drugs such as oxandrolone, although it is still metabolised by the liver and should be evaluated in that context.

Strength, Pack and Authentication

The pack contains 50 tablets of 25 mg each, sealed in moisture-resistant blister strips inside a printed carton. The carton states the compound, strength and tablet count, and a scratch-off security code inside the box links the pack to Hilma Biocare's records. Each tablet delivers a consistent 25 mg dose.

Buying Proviron Online

Proviron is one of the most searched oral support compounds. If you are researching mesterolone, comparing Proviron 25 mg products or looking to buy Proviron online from a trusted Hilma Biocare supplier, this page gives you the complete specification, pack size, price and live stock status. Browse more Hilma Biocare oral products at NotNatty.