Ipamorelin 10 mg

Ipamorelin 10 mg is Hilma Biocare's selective growth-hormone secretagogue, supplied as a single lyophilised vial. It produces clean GH pulses without significantly raising cortisol, prolactin or appetite.

What Ipamorelin Is

Ipamorelin is a pentapeptide that stimulates growth-hormone release through the ghrelin receptor. It was designed to be more selective than earlier secretagogues, and that selectivity is its defining feature: it triggers GH release without the appetite stimulation of GHRP-6 or the cortisol and prolactin increases seen with some other peptides. The 10 mg vial is the standard presentation.

The History of Ipamorelin

Ipamorelin was developed by Novo Nordisk in the 1990s and characterised in a 1998 study that described it as a selective GH secretagogue. Researchers were looking for a compound that released growth hormone without the broader hormonal effects of earlier peptides, and ipamorelin delivered that profile in animal and human studies. It became a reference peptide in GH research.

How It Works

Ipamorelin binds the ghrelin receptor on pituitary somatotrophs and activates phospholipase C, raising intracellular calcium and triggering GH release. Because it is highly selective, it does not strongly activate the pathways responsible for appetite or stress-hormone release. The peptide is rapidly cleared, producing a short pulse, and it is often studied alongside a GHRH analogue for a larger response.

What the Research Shows

• Animal and human studies show dose-dependent GH release.
• Research describes it as selective, with minimal cortisol or prolactin effect.
• Combination with GHRH analogues produces a synergistic response.
• Its short half-life is well characterised.

Research Context

Ipamorelin was designed to solve a specific problem: earlier GH secretagogues released growth hormone but also raised cortisol, prolactin and appetite. The pentapeptide was optimised for selectivity, and animal studies confirmed that it releases GH without those broader effects. That profile has made it a preferred tool in research where a clean GH pulse is the objective. It is often combined with a GHRH analogue, and the combination produces a larger and more sustained GH response than either peptide alone. That synergy has made the pairing a standard model for studying pituitary reserve and the interaction between ghrelin and GHRH signalling.

Strength, Pack and Authentication

Each vial contains 10 mg of lyophilised ipamorelin, sealed and packed in a printed carton stating the compound, strength and vial count. A scratch-off security code inside the box links the pack to Hilma Biocare's records. The powder is stable before reconstitution and intended for research use only.

Buying Ipamorelin Online

Ipamorelin is one of the most searched GH secretagogues. If you are researching ipamorelin 10 mg, comparing growth-hormone peptides or looking to buy ipamorelin online from a trusted Hilma Biocare supplier, this page gives you the full specification, pack size, price and live stock status. Browse more Hilma Biocare peptides at NotNatty.