SS-31 (Elamipretide) 10 mg

SS-31 (Elamipretide) 10 mg is Hilma Biocare's mitochondria-targeted tetrapeptide, supplied as a single lyophilised vial. It concentrates in the inner mitochondrial membrane, where it stabilises the electron transport chain.

What SS-31 Is

SS-31, also known as elamipretide, is a four-amino-acid peptide designed to target mitochondria. It binds cardiolipin, a phospholipid found almost exclusively in the inner mitochondrial membrane, and stabilises the structure of the electron transport chain. That targeted action distinguishes it from general antioxidants. The 10 mg vial is the standard presentation.

The History of SS-31

SS-31 was developed by Hazel Szeto and Peter Schiller in the 1990s and 2000s as part of a series of cell-permeable antioxidant peptides. The compounds were designed to reach mitochondria directly, and SS-31 emerged as the lead. It was licensed to Stealth BioTherapeutics and studied in heart failure, mitochondrial myopathy and age-related conditions. It remains an investigational compound.

How It Works

SS-31 enters cells and localises to the inner mitochondrial membrane, where it binds cardiolipin. That binding stabilises the electron transport chain, improves ATP production and reduces the generation of reactive oxygen species. It also helps maintain mitochondrial cristae structure. The peptide is not a generic free-radical scavenger; its effects depend on cardiolipin binding.

What the Research Shows

• Animal studies show improved mitochondrial function and ATP output.
• Research reports protection against oxidative stress and ischaemia.
• Clinical trials have examined it in heart failure and mitochondrial disease.
• Its cardiolipin-binding mechanism is well characterised.

Research Context

Elamipretide has been tested in several clinical programmes, including Barth syndrome, mitochondrial myopathy and heart failure. Results have been mixed: some trials showed improvements in functional endpoints, while others missed their primary outcomes. That inconsistency has made it a controversial compound in the mitochondrial-therapeutics field. Preclinical work continues to show benefits in models of ischaemia and oxidative stress, and the cardiolipin-binding mechanism remains a strong rationale for further study. The mixed clinical record has made SS-31 a useful case study in the gap between mitochondrial mechanisms and measurable patient outcomes, and it has encouraged researchers to look for better biomarkers of mitochondrial function.

Strength, Pack and Authentication

Each vial contains 10 mg of lyophilised SS-31, sealed and packed in a printed carton stating the compound, strength and vial count. A scratch-off security code inside the box can be checked against Hilma Biocare's records. The powder is stable before reconstitution and intended for research use only.

Buying SS-31 Online

SS-31 is one of the most searched mitochondrial peptides. If you are researching elamipretide, comparing mitochondria-targeted peptides or looking to buy SS-31 online from a trusted Hilma Biocare supplier, this page gives you the full specification, pack size, price and live stock status. Browse more Hilma Biocare longevity peptides at NotNatty.