Liothyronine T3 (Cytomel) 25 mcg

Liothyronine T3 (Cytomel) 25 mcg is Hilma Biocare's active thyroid hormone tablet, supplied as 50 tablets. T3 is the biologically active form of thyroid hormone and acts directly on metabolism without the conversion step required by T4.

What Liothyronine Is

Liothyronine is the synthetic sodium salt of triiodothyronine, the thyroid hormone that regulates basal metabolic rate, thermogenesis, protein turnover and carbohydrate and lipid metabolism. The thyroid gland produces both T4 and T3, but T3 is several times more potent at the receptor. Liothyronine is therefore the direct-acting hormone, with a faster onset and shorter half-life than levothyroxine. The 25 mcg tablet is the standard Cytomel strength.

The History of Cytomel

Thyroid hormone therapy began in the late nineteenth century with desiccated thyroid extract. Triiodothyronine was identified in the 1950s, and synthetic liothyronine was introduced soon after as Cytomel by Smith Kline and French. It was used for hypothyroidism, myxoedema and thyroid suppression, and it became a research tool for studying metabolic rate. Its rapid action made it useful where a quick onset was required.

How It Works

Liothyronine binds nuclear thyroid hormone receptors and increases the transcription of genes involved in energy metabolism, protein synthesis and thermogenesis. Because it is already the active hormone, it does not depend on deiodinase conversion, so its effects appear within hours. It has a half-life of roughly one to two days, shorter than T4. It is metabolised in the liver and peripheral tissues and excreted in bile and urine.

What the Research Shows

• Liothyronine has been studied for hypothyroidism and myxoedema.
• Research shows a faster onset and shorter half-life than levothyroxine.
• Thyroid hormone effects on metabolic rate and thermogenesis are well characterised.
• Combination T3 and T4 therapy has been investigated in thyroid research.

Research Context

Liothyronine research is closely tied to the distinction between replacement and suppression. In replacement therapy, the goal is to restore normal thyroid hormone levels; in suppression, the goal is to reduce TSH output. Studies of combination T3 and T4 therapy have produced mixed results, with some patients reporting better wellbeing on combination treatment and others showing no difference. Cardiac effects, including tachycardia and atrial fibrillation, are the main safety concern at excessive exposure, and bone turnover is affected by long-term thyroid excess.

Strength, Pack and Authentication

The pack contains 50 tablets of 25 mcg each, sealed in moisture-resistant blister strips inside a printed carton. The carton states the compound, strength and tablet count, and a scratch-off security code inside the box can be verified against Hilma Biocare's records. Each tablet delivers a consistent 25 mcg dose.

Buying T3 Online

Cytomel is one of the most searched thyroid products. If you are researching liothyronine, comparing Cytomel 25 mcg products or looking to buy T3 online from a trusted Hilma Biocare supplier, this page gives you the full specification, pack size, price and live stock status. Browse more Hilma Biocare thyroid products at NotNatty.